pentobarbital will lower the level or influence of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Potent or reasonable CYP3A4 inducers may possibly boost amount of diazepam elimination; therefore, efficacy of diazepam might be diminished.pentobarbital will lower the level or effect of ibuprofen by affec